a human osteoclast typically has five nuclei. This ruffled cell border is an extensively folded cell membrane that increases the cell surface for secretion and resorption.Ĭytologically, the osteoclasts appear to have a foamy homogenous cytoplasm because of the presence of several vesicles, vacuoles, and lysosomes filled with acid phosphatase. During an active bone resorption, the osteoclasts may appear as cells with ruffled border. The osteoclasts are located in pits in bones called Hoswhip’s lacunae that serve as resorption bays. The osteoclasts, in particular, are large, multinucleated cells that are involved in the absorption and removal of bone, particularly dissolving the fibers and the matrix of bone. The four main types of bone cells are the (1) osteoclasts, (2) osteoblasts, (3) osteocytes, and (4) lining cells. The bone cells are found within the bone tissues, and they are responsible for the make-up of the skeleton of vertebrates. The osteoclasts are a type of bone cells. ( cytology) A type of bone cell that is large, multinucleated, and associated with bone resorption
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